South Korean Defense Minister Han Min-koo said Thursday that no signs have been detected yet for the Democratic People's Republic of Korea (DPRK)'s test-firing of long- range rockets ahead of the 70th anniversary of the founding of the Worker's Party of Korea.

"Such speculations (over the DPRK's possible rocket firing) were raised at home and aboard Eric Dickerson Jersey , but there have been no such signs detected yet," Han told lawmakers during the parliamentary audit of government offices.

His comments came amid rising concerns that Pyongyang may test- fire a long-range rocket, which Seoul saw as a ballistic missile, around the 70th anniversary of the founding of the DPRK's governing party on Oct. 10.

The DPRK recently erected a 67-meter-long launch tower for long- range rockets, taller than the previous 50-meter pad, at a Tongchang-ri rocket base in the northwest DPRK. The country fired a three-stage Unha-3 rocket into the space orbit in December 2012, two months before its third nuclear test.

Tensions escalated on the Korean Peninsula last month after landmine blasts in frontline areas and the resumption of propaganda broadcasts followed by the exchange of fires across the border.

After more than 40 hours of marathon talks, Seoul and Pyongyang agreed on Aug. 25 to defuse tensions, which brought the peninsula to the brink of armed conflict, and to hold inter-governmental talks in Seoul or Pyongyang at an earliest date possible.

Foreign Minister Yun Byung-se told lawmakers that he could not rule out the possibility for the DPRK's long-range rocket fire around Oct. 10, saying that the foreign ministry would make efforts to prevent the DPRK from making any other provocations by cooperating with the international society.

Meanwhile, Minister Han said that the defense authorities were preparing for possible military talks with the DPRK as follow-up measures to the Aug. 25 agreement.

Han said that the inter-Korean military dialogue could be held as the Aug. 25 agreement promised to hold inter-government talks, noting that internal workings, including an agenda setting, were being made as such talks can happen at any time.

Research Applications For Antibody Labeling Research Applications For Antibody Labeling February 2, 2014 | Author: Marissa Velazquez | Posted in Education

Introduction: Antibody labeling is a valuable and versatile technique used in medicine and research. To put it simply, an antibody is a type of protein that an animal makes in response to a foreign antigen. This may be a bacterium, a virus or other substance present in the blood that is recognized as non-self.

There is not a single process in the mammalian body that can occur without the cooperation of one or more proteins. These are huge molecules, also known as macromolecules, that are made from smaller chemical units known as amino acids. The order in which the individual amino acids are strung together dictates the 3D shape of the finished protein. It is the specific shape of a protein that determines its function in the organism.

Enzymes are necessary to catalyze, or speed up, the millions of reactions that take place in our cells every second of every minute of every hour of every day of our lives. In fact, when we eat protein, there are enzymes that help to break down each molecule of protein into its own amino acids. These amino acids are then used to make new proteins. Immunoglobulins are a different type of protein.

Manufacture of antibodies: In the mammalian body, antibodies, also known as immunoglobulins (Igs) are synthesized by a particular type of cell in the immune system, the “B” cell. B cells are able to detect foreign molecules and produce Igs to neutralize threats. This is the basis of immunization.

There is just enough antigen present to stimulate Ig production but not enough to induce illness. If the same antigen is encountered subsequently, in other words, if the person becomes infected with virus, the B cells will be stimulated to produce loads of antibodies to quell the infection.

In the research lab, Ig synthesis begins with the injection of antigen into an animal. Rabbits are often the animal used, although other mamalian species like mice or donkeys are also used. The animal’s B cells produce antibodies to the antigen and are then harvested from their blood. Sometimes the primary antibody is conjugated to a second antibody to amplify the visual signal and then attached to a molecular probe.

More often, the primary Ig is attached to a second antibody that has been raised in a different animal, and then attached to the molecular probe, for example a fluorescent marker. When the whole three-piece molecular system is exposed to ultraviolet light, it emits fluorescence that is detected as a brilliant flash of color. Antibodies may be raised to different antigens and different colored fluorescent markers to confirm the identity of the cells to which it is later applied.

Antibody labeling is a frequently used tool in the research of neuro-oncology, or brain tumors. Cells are grown on microscope slides in a special culture medium, to which different substances, such as growth factors, may be added. The cells are then labeled with the fluorescent preparations and a snapshot is viewed of specific proteins present in the cell.

You can visit the website columbiabiosciences for more helpful information about Research Applications For Antibody Labeling

The use of liquid injections to help preserve an appearance of youth in facial skin is one of the most common plastic surgery procedures today. Dermal fillers contain different ingredients to create a youthful appearance, but BOTOX Cosmetic contains Botulinum toxin type A.

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